In a large bowl, combine the ground beef, salt, pepper, garlic powder, onion powder, and Worcestershire sauce. Mix gently to combine.

Divide the mixture into 12 equal portions and shape each portion into a small patty. Make a slight indentation in the center of each patty to help them cook evenly.

Set your Pit Boss smoker to 225°F and allow it to preheat.

For wood pellets, use hickory or mesquite for a robust, smoky flavor.

Place the patties on the grill and smoke them for about 60-90 minutes. You're looking for an internal temperature of 160°F for fully cooked patties.

During the last 5 minutes of smoking, place a slice of cheese on each patty to melt.

While the patties are smoking, prepare your toppings. Slice the pickles, onions, tomatoes, and lettuce.

Place the store-bought slider buns on the grill for a couple of minutes to get them warm and slightly crispy.

Place a smoked patty on the bottom half of each bun.

Add your desired toppings and condiments.

Top with the other half of the bun.