Fire up your grill or smoker and preheat it to 225°F (107°C).

Season the smoked brisket with your favorite dry rub or seasoning blend, ensuring it's evenly coated.

Place the brisket on the grill or smoker and let it cook low and slow for 10-12 hours, or until it reaches an internal temperature of 195°F (90°C).

Once the brisket is done, remove it from the grill and let it rest for at least 30 minutes before slicing it thinly against the grain.

Heat a skillet or griddle over medium heat.

Spread a thin layer of softened butter on one side of each slice of sourdough bread.

Place four slices of bread, butter side down, onto the skillet or griddle.

Layer each slice with cheese, followed by a generous portion of sliced smoked brisket.

If desired, add any optional toppings like caramelized onions or pickles on top of the brisket.

Top each sandwich with another slice of bread, butter side up.

Cook the sandwiches on the skillet or griddle for 3-4 minutes, or until the bottom bread slice is golden brown and crispy.

Carefully flip each sandwich using a spatula and cook for an additional 3-4 minutes on the other side until the cheese is melted and golden brown.

Remove the sandwiches from the skillet or griddle and let them cool for a minute before serving.

Slice each sandwich in half diagonally and serve hot.

Pair with your favorite sides like potato chips, coleslaw, or a crisp salad.

Dig in and savor every bite of this indulgent Smoked Brisket Grilled Cheese Sandwich!