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Smoked Brisket Grilled Cheese Sandwich

Today we’re diving into the realm of comfort food heaven with the legendary Smoked Brisket Grilled Cheese Sandwich! I mean, who doesn’t love a good grilled cheese, right? But add some juicy smoked brisket into the mix, and you’ve got yourself a whole new level of deliciousness!

smoked brisket grilled cheese sandwich

How to Make Smoked Brisket Grilled Cheese Sandwich

Alright, buckle up, because we’re about to embark on a journey to flavor town! First things first, you’re gonna need some primo ingredients:

  • Smoked brisket (the star of the show!)
  • Your favorite cheese (I’m talking gooey and melty, folks)
  • Sourdough bread (because why settle for anything less?)
  • Butter (the more, the merrier!)
  • Optional toppings like caramelized onions or pickles (get creative!)

Now, let’s get down to business:

  1. Slice up that smoked brisket nice and thin. We want it to be evenly distributed throughout our sandwich for maximum flavor in every bite!
  2. Grab two slices of sourdough bread and slather ’em with butter on one side each. We’re talkin’ golden brown perfection here, folks!
  3. Place one slice of bread, butter side down, in a hot skillet or griddle.
  4. Pile on the cheese, followed by the sliced brisket, and any other toppings your heart desires.
  5. Top it all off with the second slice of bread, butter side up, and press down gently with a spatula.
  6. Let it sizzle away until the bread is golden brown and the cheese is ooey-gooey deliciousness.
  7. Flip that bad boy over and let the other side get nice and toasty.

And there you have it, folks! A mouthwatering Smoked Brisket Grilled Cheese Sandwich that’ll have you coming back for seconds (and thirds!).

What type of wood/pellets to use for this recipe?

Ah, the age-old question of wood selection for smoking. Personally, I’m a fan of using hickory or oak for my brisket. They impart a rich, smoky flavor that pairs perfectly with the cheese and bread in this sandwich. But hey, feel free to experiment! Cherry wood or mesquite could also add some interesting flavor profiles to the mix. Just make sure whatever wood you choose is well seasoned and free of any funky flavors.

smoked brisket grilled cheese sandwich recipe

Additional Tips

Now, I’m no grill master, but I’ve picked up a few tricks along the way. Here are some extra tips to take your Smoked Brisket Grilled Cheese Sandwich game to the next level:

  • Don’t skimp on the cheese! The more, the merrier, I always say.
  • If you’re feeling fancy, you can add a smear of dijon mustard or barbecue sauce to take things up a notch.
  • For an extra crispy crust, sprinkle a little grated cheese directly onto the skillet before adding your sandwich. It’ll create a cheesy, crispy crust that’s out of this world!

What to serve

Now, what’s a sandwich without some tasty sides to accompany it? I like to keep things simple with a classic side of potato chips or a crisp dill pickle spear. But hey, if you’re feeling adventurous, you could whip up a batch of homemade coleslaw or a refreshing side salad to balance out all that cheesy goodness.

smoked brisket grilled cheese

What to do with leftovers

Now, let’s talk leftovers. If you somehow manage to have any leftover brisket (hey, stranger things have happened!), you can always repurpose it into tacos, quesadillas, or even a hearty brisket hash for breakfast. As for any leftover grilled cheese sandwiches, well, let’s just say they probably won’t last long enough to become leftovers!

Overall, folks, making a Smoked Brisket Grilled Cheese Sandwich is as much about the experience as it is about the end result. So fire up that grill, get creative with your toppings, and indulge in a little slice of comfort food paradise. And remember, there’s no such thing as too much cheese!

Smoked Brisket Grilled Cheese Sandwich

Discover the perfect combination of smoky flavors and gooey cheese in our irresistible smoked brisket grilled cheese sandwich recipe - a must-try for foodies!

Course Main Course
Prep Time 15 minutes
Cook Time 19 minutes
Servings 4


  • 1 pound smoked brisket
  • 8 slices of sourdough bread
  • 8 ounces of your favorite cheese cheddar, Swiss, or provolone work great
  • 1/4 cup butter softened
  • Optional toppings: caramelized onions pickles, dijon mustard


Preparing the Smoked Brisket (Optional: if you don't have leftover smoked brisket)

  1. Fire up your grill or smoker and preheat it to 225°F (107°C).
  2. Season the smoked brisket with your favorite dry rub or seasoning blend, ensuring it's evenly coated.
  3. Place the brisket on the grill or smoker and let it cook low and slow for 10-12 hours, or until it reaches an internal temperature of 195°F (90°C).
  4. Once the brisket is done, remove it from the grill and let it rest for at least 30 minutes before slicing it thinly against the grain.

Assembling the Sandwiches

  1. Heat a skillet or griddle over medium heat.
  2. Spread a thin layer of softened butter on one side of each slice of sourdough bread.
  3. Place four slices of bread, butter side down, onto the skillet or griddle.
  4. Layer each slice with cheese, followed by a generous portion of sliced smoked brisket.
  5. If desired, add any optional toppings like caramelized onions or pickles on top of the brisket.
  6. Top each sandwich with another slice of bread, butter side up.

Grilling the Sandwiches

  1. Cook the sandwiches on the skillet or griddle for 3-4 minutes, or until the bottom bread slice is golden brown and crispy.
  2. Carefully flip each sandwich using a spatula and cook for an additional 3-4 minutes on the other side until the cheese is melted and golden brown.
  3. Remove the sandwiches from the skillet or griddle and let them cool for a minute before serving.

Serving and Enjoying

  1. Slice each sandwich in half diagonally and serve hot.
  2. Pair with your favorite sides like potato chips, coleslaw, or a crisp salad.
  3. Dig in and savor every bite of this indulgent Smoked Brisket Grilled Cheese Sandwich!
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